Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643738 | 0.90 | LDHA (0.54) | LDHAALOX5CALM1MMP2MMP3 | |
| SCHEMBL9864987 | 0.87 | LDHA (0.51) | LDHAALOX5CALM1MMP2MMP3 | |
| SCHEMBL1856418 | 0.86 | ALDH1A1 (0.56) | LDHAALOX5MMP2MMP3MMP1 | |
| SCHEMBL156654 | 0.84 | LDHA (0.51) | LDHAALOX5CALM1MMP2MMP3 | |
| SCHEMBL3467371 | 0.82 | MMP3 (0.58) | ALOX5MMP2MMP3MMP1PDE4A | |
| SCHEMBL1861101 | 0.82 | ALDH1A1 (0.53) | ALOX5MMP2MMP3MMP1PDE4A | |
| SCHEMBL7999764 | 0.80 | LDHA (0.50) | LDHAALOX5CALM1MMP2MMP3 | |
| SCHEMBL1236958 | 0.79 | LDHA (0.56) | LDHAALOX5CALM1F2RL1ALDH1A1 | |
| SCHEMBL1238082 | 0.79 | LDHA (0.56) | LDHAALOX5CALM1F2RL1ALDH1A1 | |
| SCHEMBL1237034 | 0.79 | LDHA (0.56) | LDHAALOX5CALM1F2RL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |