Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 10/20 | 0.59 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TGM1 | P22735 | 1/20 | 0.53 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719895 | 0.88 | TGM2 (0.59) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL29505040 | 0.88 | TGM2 (0.59) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL9864586 | 0.86 | TGM2 (0.64) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL9864596 | 0.82 | ALDH1A1 (0.59) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL31596293 | 0.82 | TGM2 (0.59) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL31596038 | 0.82 | TGM2 (0.59) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL9937593 | 0.80 | HTT (0.66) | LMNACYP19A1HTTMEN1KMT2A | |
| SCHEMBL9995213 | 0.79 | LMNA (0.62) | TGM2LMNAHTTMEN1KMT2A | |
| SCHEMBL22719492 | 0.79 | KMT2A (0.62) | TGM2LMNAMEN1KMT2ARAB9A | |
| SCHEMBL29505028 | 0.79 | KMT2A (0.62) | TGM2LMNAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409565-A1 | Rubber composition useful for tires | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-23 | — | — | EP | disclosed |