Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28086313 | 0.98 | NPC1 (0.64) | NPC1RAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL10417608 | 0.92 | ADRB2 (0.58) | NPC1RAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL10645075 | 0.86 | EPHX2 (0.58) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL8781424 | 0.85 | SIGMAR1 (0.55) | NPC1RAB9AALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL9838744 | 0.84 | HPGD (0.57) | NPC1RAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL23775472 | 0.82 | CRHBP (0.51) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL9444390 | 0.81 | MEN1 (0.63) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL10642628 | 0.80 | ADRB2 (0.57) | NPC1RAB9AALDH1A1HPGDHTT | |
| Hydrochloric Acid SCHEMBL9444319 | 0.80 | MEN1 (0.62) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL22106122 | 0.80 | HPGD (0.71) | NPC1RAB9AALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996215-A | Antiarrythmia agents | EISAI CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |