Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865814 | 0.89 | MCHR1 (0.36) | MCHR1TOP1HRH3 | |
| Iodide SCHEMBL9866676 | 0.87 | HRH3 (0.34) | HRH3KMT2A | |
| SCHEMBL9603115 | 0.83 | MCHR1 (0.48) | MCHR1TOP1HRH3KMT2A | |
| SCHEMBL9602979 | 0.80 | MCHR1 (0.43) | MCHR1TOP1HRH3KMT2A | |
| SCHEMBL9865298 | 0.80 | MCHR1 (0.43) | MCHR1TOP1HRH3KMT2A | |
| SCHEMBL10445226 | 0.79 | MCHR1 (0.42) | MCHR1TOP1HRH3KMT2A | |
| SCHEMBL9867236 | 0.78 | MCHR1 (0.44) | MCHR1TOP1HRH3KMT2A | |
| SCHEMBL10561567 | 0.77 | LMNA (0.41) | KMT2A | |
| SCHEMBL9866095 | 0.77 | MCHR1 (0.43) | MCHR1TOP1HRH3KMT2A | |
| SCHEMBL9866270 | 0.76 | MCHR1 (0.42) | MCHR1TOP1HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |