Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865029 | 0.87 | MCHR1 (0.42) | HRH3KMT2A | |
| Iodide SCHEMBL10445057 | 0.83 | HRH3 (0.43) | HRH3KMT2A | |
| SCHEMBL9866678 | 0.82 | HRH3 (0.44) | HRH3KMT2A | |
| Iodide SCHEMBL10445020 | 0.80 | ALDH1A1 (0.35) | HRH3KMT2A | |
| SCHEMBL9865898 | 0.79 | CA12 (0.35) | HRH3KMT2A | |
| SCHEMBL10561567 | 0.77 | LMNA (0.41) | KMT2A | |
| SCHEMBL9865814 | 0.76 | MCHR1 (0.36) | HRH3 | |
| SCHEMBL9865213 | 0.75 | HRH3 (0.37) | HRH3KMT2A | |
| Iodide SCHEMBL10445022 | 0.75 | ALDH1A1 (0.39) | HRH3KMT2A | |
| SCHEMBL9867010 | 0.73 | ALDH1A1 (0.39) | HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |