Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864453 | 0.77 | GRIA4 (0.45) | MAPTMAOAMAOBL3MBTL1PLA2G1B | |
| SCHEMBL7861798 | 0.69 | MAOA (0.56) | MAPTMAOAMAOBL3MBTL1PLA2G1B | |
| SCHEMBL27275585 | 0.68 | ADORA1 (0.36) | — | |
| SCHEMBL9865724 | 0.67 | MEN1 (0.32) | MAPTALDH1A1HPGD | |
| SCHEMBL27275583 | 0.67 | MAPT (0.43) | MAPTL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL10654822 | 0.66 | ALDH1A1 (0.39) | L3MBTL1LMNAGRM6KDM4EALDH1A1 | |
| SCHEMBL9865016 | 0.65 | FNTA (0.39) | MAPTL3MBTL1GRIA4LMNATDP1 | |
| SCHEMBL9865004 | 0.64 | MAOA (0.42) | MAPTMAOAMAOBL3MBTL1PLA2G1B | |
| SCHEMBL27275581 | 0.64 | — | — | |
| SCHEMBL7106251 | 0.63 | MAOA (0.48) | MAPTMAOAMAOBL3MBTL1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |