Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652965 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10ADORA2A | |
| SCHEMBL10654927 | 0.84 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2HPGDSQOR | |
| SCHEMBL10655997 | 0.83 | ADORA1 (0.42) | ALDH1A1KDM4EHPGDADORA2AADORA1 | |
| SCHEMBL10656293 | 0.82 | PRKCZ (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDSQOR | |
| SCHEMBL10658430 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10ADORA2A | |
| SCHEMBL11948739 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2HPGDSQOR | |
| SCHEMBL9527695 | 0.73 | ADORA1 (0.41) | ALDH1A1KDM4ESMN1; SMN2HPGDSQOR | |
| SCHEMBL9422075 | 0.73 | PRKCZ (0.55) | ALDH1A1KDM4EHPGDHSD17B10ADORA2A | |
| SCHEMBL10655060 | 0.72 | GRIA4 (0.47) | ALDH1A1KDM4ESMN1; SMN2HPGDSQOR | |
| SCHEMBL10745834 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HPGDL3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |