Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864840 | 0.66 | CA2 (0.33) | CA2 | |
| SCHEMBL22905505 | 0.58 | CA2 (0.39) | CA2 | |
| SCHEMBL27490921 | 0.56 | CA2 (0.43) | CA2 | |
| SCHEMBL29567136 | 0.55 | CA2 (0.33) | CA2 | |
| SCHEMBL22905483 | 0.55 | CA2 (0.33) | CA2 | |
| SCHEMBL22638694 | 0.54 | KMT2A (0.49) | CA2 | |
| SCHEMBL22638674 | 0.54 | TTR (0.46) | CA2 | |
| SCHEMBL18007542 | 0.53 | CA2 (0.40) | CA2 | |
| SCHEMBL10508576 | 0.52 | CA2 (0.66) | CA2 | |
| SCHEMBL19475512 | 0.52 | CA2 (0.37) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045561-A | Substituted furan sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1991-09-03 | — | — | US | disclosed |
| US-4863922-A | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use | MERCK & CO., INC. (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0296879-A1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1988-12-28 | — | — | EP | disclosed |