Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602957 | 0.95 | PTGS1 (0.42) | ADRB2ADRB1ADRB3PTGS1SLC6A2 | |
| SCHEMBL9866651 | 0.95 | ADRB2 (0.45) | ADRB2ADRB1ADRB3PTGS1SLC6A2 | |
| SCHEMBL9865872 | 0.92 | ADRB2 (0.44) | ADRB2ADRB1ADRB3HRH3PTGS1 | |
| SCHEMBL9603116 | 0.84 | CYP2D6 (0.41) | ADRB2ADRB1ADRB3MAPK14MAPK13 | |
| SCHEMBL9601550 | 0.80 | HRH3 (0.40) | HRH3MAPK14MAPK13HSPB1HTR2A | |
| SCHEMBL9602367 | 0.80 | ATM (0.47) | — | |
| SCHEMBL9601997 | 0.79 | HRH3 (0.39) | HRH3MAPK14MAPK13HSPB1HTR2A | |
| SCHEMBL9602826 | 0.79 | ATM (0.48) | — | |
| SCHEMBL9602470 | 0.79 | KDM4E (0.51) | — | |
| SCHEMBL9602093 | 0.78 | HRH3 (0.39) | HRH3MAPK14MAPK13HSPB1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |