Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469506 | 0.78 | EPHX1 (0.55) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL252017 | 0.78 | EPHX1 (0.55) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL6545341 | 0.74 | EPHX1 (0.64) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL564024 | 0.74 | EPHX1 (0.50) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL6282853 | 0.74 | EPHX1 (0.50) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL66064 | 0.74 | SIGMAR1 (0.58) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL219294 | 0.74 | EPHX1 (0.50) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL1278885 | 0.74 | EPHX1 (0.50) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL5146904 | 0.74 | EPHX1 (0.50) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL707068 | 0.74 | EPHX1 (0.50) | EPHX1TAAR1SLC6A2SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| WO-1982001186-A1 | NOVEL BENZOXAZOLINONES,SUBSTITUTED IN THE 6-POSITION BY AN AMINOALCOHOL CHAIN OR AMINO-KETONE CHAIN,THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL PREPARATIONS | BUSCH N | 1982-04-15 | — | — | WO | disclosed |