Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278885 | 0.79 | EPHX1 (0.50) | EPHX1CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL1833632 | 0.78 | EPHX1 (0.55) | EPHX1CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL252017 | 0.78 | EPHX1 (0.55) | EPHX1CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL11741416 | 0.78 | EPHX1 (0.55) | EPHX1CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL10514103 | 0.76 | EPHX1 (0.52) | EPHX1CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL28858558 | 0.75 | EPHX1 (0.46) | EPHX1CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL6832904 | 0.75 | IDO1 (0.42) | CYP1A2TAAR1CYP2A6 | |
| SCHEMBL10544290 | 0.75 | CYP1A2 (0.46) | EPHX1CYP1A2ALPIPKMPTGS1 | |
| SCHEMBL8378873 | 0.75 | TDP1 (0.48) | TAAR1CYP2A6ALDH1A1TSHRANPEP | |
| SCHEMBL6465862 | 0.75 | CPA3 (0.60) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768307-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3100723-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-2785178-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20190023649-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | BIKAM PHARMACEUTICALS, INC. (US) | 2019-01-24 | — | — | US | disclosed |
| EP-2720539-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2018-10-24 | — | — | EP | disclosed |
| US-10040749-B2 | Opsin-binding ligands, compositions and methods of use | BIKAM PHARMACEUTICALS INC. (US) | 2018-08-07 | — | — | US | disclosed |
| CN-103917093-B | Opsin binding ligands, compositions, and methods of use | 比卡姆药品公司 | 2017-08-11 | — | — | CN | disclosed |
| US-20170137398-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2017-05-18 | — | — | US | disclosed |
| CN-106431988-A | Opsin-binding ligands, compositions and methods of use | 比卡姆药品公司 | 2017-02-22 | — | — | CN | disclosed |
| US-20170037024-A1 | Opsin-Binding Ligands, Compositions and Methods for Use | BIKAM PHARMACEUTICALS, INC. (US) | 2017-02-09 | — | — | US | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |
| CN-86103619-A | The preparation method of the bicyclic pyrazolidinones that 7-replaces | — | 1986-10-29 | — | — | CN | disclosed |
| US-4423203-A | Electrically photosensitive polymers containing vinylene-1,4-phenylene-imino-1,4-phenylene-vinylenearylene groups | EASTMAN KODAK COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0067217-A4 | COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER. | GEN ELECTRIC (US) | 1983-05-16 | — | — | EP | disclosed |
| EP-0067217-A1 | COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER | GENERAL ELECTRIC COMPANY (US) | 1982-12-22 | — | — | EP | disclosed |
| US-4365042-A | Compositions of polyphenylene oxides with EPDM-silicone rubber | GENERAL ELECTRIC COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| WO-1982002204-A1 | COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER | GEN ELECTRIC (US) | 1982-07-08 | — | — | WO | disclosed |
| US-4304693-A | Semisolid water-based coating compositions | PPG INDUSTRIES, INC. (US) | 1981-12-08 | — | — | US | disclosed |
| US-4174228-A | SPRAYABLE FIREPROOFING MATERIAL | PPG INDUSTRIES, INC. (US) | 1979-11-13 | — | — | US | disclosed |
| US-4174229-A | SPRAYABLE FIREPROOFING MATERIAL | PPG INDUSTRIES, INC. (US) | 1979-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137398-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | CRYAB, CRYAA, PDE6C | EPHX1 3866/4885CYP1A2 4420/4885ALPI 4637/4885 |
| US-20170037024-A1 | Opsin-Binding Ligands, Compositions and Methods for Use | CRYAB, CRYAA, PDE6C | EPHX1 3824/4885CYP1A2 4455/4885ALPI 4630/4885 |
| US-10040749-B2 | Opsin-binding ligands, compositions and methods of use | CRYAB, CRYAA, PDE6C | EPHX1 3829/4885CYP1A2 4463/4885ALPI 4644/4885 |
| US-20190023649-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | CRYAB, CRYAA, PDE6C | EPHX1 3829/4885CYP1A2 4463/4885ALPI 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.