Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865611 | 1.00 | FAAH (0.52) | FAAHKDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL9593815 | 0.83 | FAAH (0.49) | FAAHHRH2HRH3 | |
| SCHEMBL9593812 | 0.83 | FAAH (0.49) | FAAHHRH2HRH3 | |
| SCHEMBL9865051 | 0.81 | SCN5A (0.59) | ALDH1A1 | |
| SCHEMBL9865046 | 0.81 | SCN5A (0.59) | ALDH1A1 | |
| SCHEMBL9593372 | 0.80 | FAAH (0.49) | FAAHHRH2HRH3 | |
| SCHEMBL9593379 | 0.80 | FAAH (0.49) | FAAHHRH2HRH3 | |
| SCHEMBL9865624 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL10837381 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL9867943 | 0.78 | KDM4E (0.47) | FAAHKDM4EALDH1A1HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |