Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675163 | 0.84 | HRH2 (0.67) | KDM4EALDH1A1HRH2HRH3 | |
| Hydrochloric Acid SCHEMBL10675153 | 0.83 | HRH2 (0.66) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL10837381 | 0.83 | KDM4E (0.74) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL9593817 | 0.83 | HRH2 (0.55) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL9865059 | 0.81 | RAB9A (0.55) | — | |
| SCHEMBL9593382 | 0.80 | HRH2 (0.52) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL11086396 | 0.80 | KDM4E (0.75) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL9865611 | 0.80 | FAAH (0.52) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL9865618 | 0.80 | FAAH (0.52) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL11185887 | 0.79 | HRH2 (0.78) | KDM4EALDH1A1HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |