Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 4/20 | 0.59 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865051 | 1.00 | SCN5A (0.59) | SCN5ASCN2ARAB9ANPC1HPGD | |
| SCHEMBL4629193 | 0.82 | SCN5A (0.83) | SCN5ASCN2ARAB9ANPC1HPGD | |
| SCHEMBL9865611 | 0.81 | FAAH (0.52) | ALDH1A1 | |
| SCHEMBL4629278 | 0.74 | SCN2A (1.00) | SCN5ASCN2ANPC1SMN1; SMN2CACNA1H | |
| SCHEMBL4629480 | 0.74 | SCN2A (0.80) | SCN5ASCN2ARAB9ACACNA1HALDH1A1 | |
| SCHEMBL9866781 | 0.72 | SCN5A (0.46) | SCN5ASCN2ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9866787 | 0.72 | SCN5A (0.46) | SCN5ASCN2ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9344656 | 0.71 | ALDH1A1 (0.72) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL16293318 | 0.70 | ALDH1A1 (0.52) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9865059 | 0.70 | RAB9A (0.55) | RAB9ANPC1HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |