Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865610 | 0.85 | HDAC3 (0.49) | HDAC3HDAC1L3MBTL1MAPTPOLB | |
| SCHEMBL7310718 | 0.82 | CYP3A4 (0.56) | HDAC3HDAC1L3MBTL1MAPTPOLB | |
| SCHEMBL9335827 | 0.82 | CA1 (0.45) | HDAC3HDAC1L3MBTL1MAPTPOLB | |
| SCHEMBL9865803 | 0.81 | ALDH1A1 (0.49) | HDAC3HDAC1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL9339394 | 0.80 | CA1 (0.51) | HDAC3HDAC1L3MBTL1MAPTPOLB | |
| SCHEMBL7298164 | 0.79 | HTT (0.54) | HDAC3HDAC1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL4924340 | 0.79 | HTT (0.56) | L3MBTL1MAPTPOLBMAPK1MEN1 | |
| SCHEMBL17599919 | 0.79 | CYP3A4 (0.59) | HDAC3HDAC1L3MBTL1MAPTPOLB | |
| SCHEMBL23777326 | 0.78 | TPSAB1 (0.56) | L3MBTL1MAPTPOLBMAPK1MEN1 | |
| SCHEMBL2417332 | 0.78 | TPSAB1 (0.56) | L3MBTL1MAPTPOLBMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |