Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851664 | 0.85 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL11853981 | 0.83 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL2296409 | 0.82 | TMPRSS4 (0.56) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL27754113 | 0.81 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL27538372 | 0.81 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9868029 | 0.78 | HSPD1 (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL13656899 | 0.77 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL12305575 | 0.75 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL28778645 | 0.75 | CXCR2 (0.63) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL28797060 | 0.74 | KMT2A (0.50) | MEN1KMT2ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |