SCHEMBL2296409

SCHEMBL2296409

O=C(Nc1ccccc1)c1cc(Cl)c(Cl)c(Cl)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMPRSS4 Q9NRS4 1/20 0.56
HSPD1 P10809 1/20 0.55
HSPE1 P61604 1/20 0.55
STK39 Q9UEW8 1/20 0.53
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
LMNA P02545 2/20 0.53
TP53 P04637 2/20 0.53
HTT P42858 2/20 0.53
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53
HSD17B10 Q99714 1/20 0.53
BCL2 P10415 2/20 0.52
PPARG P37231 2/20 0.52
MAPT P10636 3/20 0.50
MAPK1 P28482 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP2C19 P33261 2/20 0.50
GPR27 Q9NS67 2/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11797903 0.87 P2RX1 (0.59) TMPRSS4STK39MEN1KMT2ALMNA
SCHEMBL8009293 0.87 PPARG (0.58) TMPRSS4MEN1KMT2ALMNATP53
SCHEMBL9868029 0.86 HSPD1 (0.55) TMPRSS4HSPD1HSPE1STK39MEN1
SCHEMBL10359778 0.86 HSPD1 (0.63) HSPD1HSPE1MEN1KMT2ALMNA
SCHEMBL11793710 0.84 KMT2A (0.61) HSPD1HSPE1STK39MEN1KMT2A
SCHEMBL13656899 0.83 MEN1 (0.66) TMPRSS4HSPD1HSPE1STK39MEN1
SCHEMBL11791152 0.82 P2RX1 (0.55) TMPRSS4HSPD1HSPE1STK39MEN1
SCHEMBL28091035 0.82 GPR27 (0.57) TMPRSS4MEN1KMT2ALMNATP53
SCHEMBL9865757 0.82 MEN1 (0.59) TMPRSS4HSPD1HSPE1STK39MEN1
SCHEMBL9868077 0.81 STK39 (0.77) TMPRSS4STK39MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115916147-A Anti-acne composition 欧莱雅 2023-04-04 CN claimed
EP-2875141-A1 ANTIMICROBIAL AGENTS Bedoukian Research, Inc. (US) 2015-05-27 EP claimed
US-20150125402-A1 ANTIMICROBIAL AGENTS BEDOUKIAN RESEARCH, INC. 2015-05-07 US claimed
WO-2014014490-A1 ANTIMICROBIAL AGENTS BEDOUKIAN RESEARCH, INC. (US) 2014-01-23 WO claimed
EP-0868756-A4 ELECTROCHEMICAL CELL WITH A NON-LIQUID ELECTROLYTE E C R ELECTRO CHEMICAL RES LTD (IL) 2003-09-10 EP claimed
US-20020122980-A1 Can be used as power sources for storage and release of electrical energy such as batteries, capacitors and hybrid electrochemical cells termed batcaps FLEISCHER NILES A (IL) 2002-09-05 US claimed
EP-0938288-B1 PERFUMED PRODUCTS QUEST INT (NL) 2002-03-27 EP claimed
JP-2002507310-A 2002-03-05 JP claimed
US-6241979-B1 Perfumed products containing a mixture of perfume materials having antibacterial properties QUEST INTERNATIONAL B.V. (NL) 2001-06-05 US claimed
EP-0938288-A1 PERFUMED PRODUCTS QUEST INTERNATIONAL B.V. (NL) 1999-09-01 EP claimed
EP-0868756-A1 ELECTROCHEMICAL CELL WITH A NON-LIQUID ELECTROLYTE E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-10-07 EP claimed
WO-1998016194-A1 PERFUMED PRODUCTS QUEST INTERNATIONAL B.V. (NL) 1998-04-23 WO claimed
WO-1998013887-A1 ELECTROCHEMICAL CELL WITH A NON-LIQUID ELECTROLYTE E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-04-02 WO claimed
US-5731105-A Battery electrochemical cell with a non-liquid electrolyte E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-03-24 US claimed
JP-64000012-A None JP disclosed
WO-2025069748-A1 METHOD FOR PRODUCING AZELAIC ACID PARTICLES, AND EXTERNAL PREPARATION FOR SKIN 株式会社NIKU 2025-04-03 WO disclosed
CN-119365547-A Particles for forming pickering emulsions and the like 麒麟控股株式会社 2025-01-24 CN disclosed
EP-0300286-A2 Multilayer sandwich sheet and its use in packaging FIRMENICH SA (CH) 1989-01-25 EP disclosed
JP-S6412-A AROMA-IMPARTING COMPOSITION HAVING DEODORANT OR PERSPIRATION-SUPPRESSING ACTION AND DEODORANT OR PERSPIRATION-SUPPRESSING PRODUCT FIRMENICH SA 1989-01-05 JP disclosed
EP-0279328-A2 Perfuming composition with a deodorizing or antiperspirant activity FIRMENICH SA (CH) 1988-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150125402-A1 ANTIMICROBIAL AGENTS SOD1, ERG28, ARG1 TMPRSS4 3908/4885HSPD1 1048/4885HSPE1 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.