Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | BCL2 | P10415 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.50 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296409 | 0.86 | TMPRSS4 (0.56) | HSPD1HSPE1DHODHMEN1KMT2A | |
| SCHEMBL13656899 | 0.79 | MEN1 (0.66) | HSPD1HSPE1DHODHMEN1KMT2A | |
| SCHEMBL28091035 | 0.78 | GPR27 (0.57) | MEN1KMT2ATMPRSS4BCL2HPGD | |
| SCHEMBL4359810 | 0.78 | MEN1 (0.56) | MEN1KMT2ALMNATP53KDM4E | |
| SCHEMBL9865757 | 0.78 | MEN1 (0.59) | HSPD1HSPE1MEN1KMT2ATMPRSS4 | |
| SCHEMBL9868077 | 0.77 | STK39 (0.77) | TMPRSS4STK39MAPK1 | |
| SCHEMBL27733378 | 0.77 | HTT (0.56) | HSPD1HSPE1MEN1KMT2ATMPRSS4 | |
| SCHEMBL8009293 | 0.76 | PPARG (0.58) | MEN1KMT2ATMPRSS4HPGDGPR27 | |
| Hydrochloric Acid SCHEMBL11777767 | 0.76 | STK39 (0.75) | TMPRSS4STK39MAPK1 | |
| SCHEMBL2149302 | 0.76 | AKR1C2 (0.52) | MEN1KMT2AHPGDTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |