SCHEMBL9865758

SCHEMBL9865758

N#Cc1sc([S+]([O-])c2ccccc2)c(C#N)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM6 O15303 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9866005 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9865724 0.74 MEN1 (0.32) ALDH1A1
SCHEMBL20359 0.70
SCHEMBL9866238 0.68
SCHEMBL9865004 0.67 MAOA (0.42) ALDH1A1
SCHEMBL10572170 0.67 CDC7 (0.33) ALDH1A1
SCHEMBL9865543 0.66
SCHEMBL9864847 0.66 KDM4E (0.33) GRM6ALDH1A1
SCHEMBL8257217 0.65
SCHEMBL9865594 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4994485-A Seed and soil fungi, bacteria DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1991-02-19 US disclosed
EP-0234622-B1 NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1990-06-27 EP disclosed
EP-0234622-A1 New thio compounds having fungicidal activity DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1987-09-02 EP disclosed