Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866040 | 0.82 | GRIA4 (0.37) | ALDH1A1MAPK1HTTGRIA4KDM4E | |
| SCHEMBL9493186 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPK1HTTGRIA4GRIA2 | |
| SCHEMBL6644214 | 0.71 | GRIA4 (0.47) | ALDH1A1MAPK1HTTGRIA4GRIA2 | |
| SCHEMBL9864594 | 0.71 | GRIA4 (0.47) | ALDH1A1MAPK1HTTGRIA4GRIA2 | |
| SCHEMBL3818516 | 0.71 | GRIA4 (0.57) | ALDH1A1MAPK1HTTGRIA4GRIA2 | |
| SCHEMBL9865743 | 0.70 | — | — | |
| SCHEMBL3401657 | 0.69 | GRIA4 (0.45) | ALDH1A1HTTGRIA4GRIA2KDM4E | |
| SCHEMBL10298787 | 0.66 | GRM6 (0.45) | ALDH1A1MAPK1HTTKDM4ENPSR1 | |
| SCHEMBL623739 | 0.65 | L3MBTL1 (0.53) | ALDH1A1KDM4ENPSR1L3MBTL1 | |
| SCHEMBL9865632 | 0.64 | MEN1 (0.70) | ALDH1A1MAPK1HTTGRIA4GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |