Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549634 | 0.90 | LMNA (0.45) | GAAALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL2943216 | 0.89 | LMNA (0.43) | GAAALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL4625614 | 0.87 | CYP2A6 (0.44) | GAAALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7621560 | 0.87 | KDM4E (0.46) | GAAALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL29251851 | 0.86 | HTT (0.44) | GAAALDH1A1KDM4ELMNACYP3A4 | |
| Sulfuric Acid SCHEMBL21195058 | 0.86 | HTT (0.44) | GAAALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL143552 | 0.86 | MAPT (0.46) | GAAALDH1A1KDM4EMAPTLMNA | |
| Sulfuric Acid SCHEMBL21195059 | 0.85 | HTT (0.42) | GAAALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL2639726 | 0.84 | HTT (0.58) | LMNACYP2D6CYP2C9CYP2C19HTT | |
| SCHEMBL2150381 | 0.84 | ALDH1A1 (0.44) | GAAALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003077-A | Having a cycloheptimidazole nucleus; photostability; methine bond having an auxochrome | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-26 | — | — | US | disclosed |