Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 3/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866013 | 0.90 | RAB9A (0.47) | BRD4CYP2C9PTGER1SMPD1HDAC1 | |
| SCHEMBL7342794 | 0.85 | BRD4 (0.68) | RXRABRD4RXRBRXRGCYP2C9 | |
| SCHEMBL9339420 | 0.83 | BRD4 (0.50) | BRD4CYP2C9PTGER1SMPD1HDAC1 | |
| SCHEMBL566467 | 0.83 | CREBBP (0.60) | HDAC1HDAC8HDAC6POLBMAPT | |
| SCHEMBL15831277 | 0.82 | MEN1 (0.66) | POLBMAPT | |
| SCHEMBL12994195 | 0.81 | BRD4 (0.56) | BRD4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL30362191 | 0.81 | PPARG (0.55) | HDAC1HDAC8HDAC6PPARGPPARA | |
| SCHEMBL3982009 | 0.81 | PPARG (0.55) | HDAC1HDAC8HDAC6PPARGPPARA | |
| SCHEMBL6279532 | 0.81 | BRD4 (0.48) | BRD4CYP2C9PTGER1MRGPRX4HDAC1 | |
| SCHEMBL11959262 | 0.81 | BRD4 (0.51) | BRD4CYP2C9PTGER1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |