Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865892 | 0.90 | RXRA (0.49) | CYP2C9PTGER1BRD4SMPD1HDAC1 | |
| SCHEMBL20401090 | 0.84 | RAB9A (0.54) | RAB9ACYP2C9BRD4KMT2AGAA | |
| SCHEMBL12994195 | 0.83 | BRD4 (0.56) | RAB9ABRD4LMNASMPD1HDAC1 | |
| SCHEMBL7342794 | 0.82 | BRD4 (0.68) | RAB9ACYP2C9PTGER1BRD4KMT2A | |
| SCHEMBL9339420 | 0.81 | BRD4 (0.50) | RAB9ACYP2C9PTGER1BRD4KMT2A | |
| SCHEMBL9865773 | 0.80 | MEN1 (0.47) | RAB9ACYP2C9PTGER1KMT2AGAA | |
| SCHEMBL7477944 | 0.80 | KMT2A (0.66) | RAB9AKMT2AGAALMNASLC6A2 | |
| SCHEMBL7425443 | 0.79 | RAB9A (0.71) | RAB9ACYP2C9KMT2AGAASLC6A2 | |
| SCHEMBL15831277 | 0.79 | MEN1 (0.66) | KMT2AGAALMNAALDH1A1MAPT | |
| SCHEMBL8650559 | 0.79 | RAB9A (0.56) | RAB9AKMT2AGAALMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |