Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 3/20 | 0.35 |
| ▸ | FNTB | P49356 | 3/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865250 | 0.87 | LMNA (0.42) | LMNAHPGDALDH1A1KDM4EGAA | |
| SCHEMBL9865195 | 0.85 | LMNA (0.52) | LMNAHPGDALDH1A1KDM4EGAA | |
| SCHEMBL9865339 | 0.81 | FNTA (0.32) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9865338 | 0.80 | MEN1 (0.41) | LMNAHPGDALDH1A1KDM4EGAA | |
| SCHEMBL9864548 | 0.78 | ALDH1A1 (0.42) | LMNAHPGDALDH1A1KDM4EGAA | |
| SCHEMBL9866096 | 0.75 | ALDH1A1 (0.42) | LMNAHPGDALDH1A1KDM4EGAA | |
| SCHEMBL9865163 | 0.74 | MAPT (0.40) | LMNAHPGDALDH1A1KDM4EGAA | |
| SCHEMBL9865539 | 0.74 | ALDH1A1 (0.54) | LMNAHPGDALDH1A1KDM4EGAA | |
| SCHEMBL9864464 | 0.71 | — | — | |
| SCHEMBL9866197 | 0.71 | L3MBTL1 (0.32) | HPGDALDH1A1KDM4EMELKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |