Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | UTRN | P46939 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869122 | 0.88 | NPC1 (0.51) | NPC1KIF11PTPN2PTPN1PTPN5 | |
| SCHEMBL1026246 | 0.82 | PIK3CB (0.50) | NPC1KIF11PTPN2PTPN1PTPN5 | |
| SCHEMBL18935939 | 0.80 | TLR9 (0.55) | NPC1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL4157253 | 0.80 | PTPN2 (0.68) | NPC1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL23172360 | 0.80 | ALDH1A1 (0.47) | NPC1HDAC6HSD17B10MEN1ALDH1A1 | |
| SCHEMBL218776 | 0.80 | NPC1 (0.63) | NPC1HSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL9867106 | 0.80 | NPC1 (0.52) | NPC1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL9868967 | 0.79 | ALDH1A1 (0.63) | NPC1HSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL25026542 | 0.79 | HDAC3 (0.60) | NPC1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL1023498 | 0.79 | PIK3CB (0.61) | NPC1KIF11PTPN2PTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |