Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | UTRN | P46939 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866061 | 0.88 | NPC1 (0.51) | NPC1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL23458516 | 0.85 | PIK3CB (0.60) | NPC1HDAC6PIK3CBPIK3CAHSD17B10 | |
| SCHEMBL30785563 | 0.83 | ALDH1A1 (0.48) | NPC1HDAC6PTPN2PTPN1PTPN5 | |
| SCHEMBL1023498 | 0.82 | PIK3CB (0.61) | NPC1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL321652 | 0.80 | HDAC6 (0.49) | NPC1HDAC6PTPN2PTPN1PTPN5 | |
| SCHEMBL9868132 | 0.80 | KDM4E (0.56) | NPC1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL4157253 | 0.80 | PTPN2 (0.68) | NPC1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL222248 | 0.80 | RAB9A (0.63) | NPC1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL30785580 | 0.80 | KDM4E (0.56) | NPC1PTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL2246415 | 0.80 | NPC1 (0.63) | NPC1PTPN2PTPN1PTPN5PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |