Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335792 | 0.82 | LTA4H (0.46) | LTA4HRAB9ANPC1ESRRAGAA | |
| SCHEMBL9866032 | 0.79 | CA1 (0.50) | LTA4HRAB9ANPC1LRRK2HDAC1 | |
| SCHEMBL9335876 | 0.78 | LTA4H (0.44) | LTA4HRAB9ANPC1GAALRRK2 | |
| SCHEMBL9335827 | 0.78 | CA1 (0.45) | LTA4HLRRK2KMT2AHDAC1HDAC2 | |
| SCHEMBL9337569 | 0.77 | LTA4H (0.54) | LTA4HRAB9ANPC1GAALRRK2 | |
| SCHEMBL9337449 | 0.76 | CA1 (0.47) | LTA4HRAB9ANPC1LRRK2HDAC1 | |
| SCHEMBL9865773 | 0.75 | MEN1 (0.47) | LTA4HRAB9ANPC1ESRRAGAA | |
| SCHEMBL1646770 | 0.73 | LRRK2 (0.56) | LRRK2KMT2A | |
| SCHEMBL14264247 | 0.73 | HTT (0.64) | LTA4HHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL23809724 | 0.72 | ALDH1A1 (0.62) | RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |