Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20418351 | 0.91 | RAB9A (0.48) | MEN1KMT2ACYP2C9PTGER1GAA | |
| SCHEMBL29447700 | 0.91 | RAB9A (0.48) | MEN1KMT2ACYP2C9PTGER1GAA | |
| SCHEMBL9865221 | 0.90 | FOLH1 (0.53) | MEN1KMT2ACYP2C9PTGER1GAA | |
| SCHEMBL15055245 | 0.84 | RAB9A (0.54) | KMT2ACYP2C9GAARAB9ANPC1 | |
| SCHEMBL19511313 | 0.83 | C5AR1 (0.44) | MEN1KMT2ACYP2C9PTGER1GAA | |
| SCHEMBL20400859 | 0.83 | NPC1 (0.51) | MEN1KMT2ACYP2C9PTGER1GAA | |
| SCHEMBL10152859 | 0.83 | ALDH1A1 (0.57) | MEN1KMT2ACYP2C9PTGER1GAA | |
| SCHEMBL15055137 | 0.83 | RAB9A (0.46) | KMT2ACYP2C9GAARAB9ANPC1 | |
| SCHEMBL9335648 | 0.81 | LRRK2 (0.46) | MEN1KMT2ACYP2C9PTGER1GAA | |
| SCHEMBL9866013 | 0.80 | RAB9A (0.47) | MEN1KMT2ACYP2C9PTGER1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |