Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867255 | 0.89 | ALDH1A1 (0.37) | CYP2C19KMT2ACYP1A2POLBNPSR1 | |
| SCHEMBL9866816 | 0.83 | SLC47A1 (0.36) | CYP2C19CYP2D6KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL9866194 | 0.83 | SLC47A1 (0.36) | CYP2C19CYP2D6KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL10872563 | 0.83 | — | — | |
| SCHEMBL9866169 | 0.83 | SLC47A1 (0.36) | CYP2C19CYP2D6KMT2ACYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9865304 | 0.82 | L3MBTL1 (0.37) | CYP2C19CYP2D6KMT2ACYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9866175 | 0.82 | L3MBTL1 (0.37) | CYP2C19CYP2D6KMT2ACYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10874476 | 0.82 | L3MBTL1 (0.37) | CYP2C19CYP2D6KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL9866870 | 0.81 | MTNR1A (0.44) | CYP2C19CYP2D6KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL9866299 | 0.81 | HRH4 (0.37) | EPHX2CYP2C9CYP2C19CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0199845-B1 | IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |