Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | HTR3A | P46098 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865649 | 0.88 | DRD2 (0.57) | DRD4DRD2DRD3HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL9866290 | 0.87 | DRD2 (0.56) | DRD4DRD2DRD3HTR3AKCNH2 | |
| SCHEMBL9867444 | 0.84 | DRD4 (0.77) | DRD4DRD2DRD3HTR3AKCNH2 | |
| SCHEMBL9868067 | 0.82 | MLNR (0.55) | DRD2DRD3HTR3AKCNH2MLNR | |
| SCHEMBL9866832 | 0.81 | DRD2 (0.54) | DRD4DRD2DRD3HTR3AKCNH2 | |
| SCHEMBL9867361 | 0.81 | DRD2 (0.67) | DRD4DRD2DRD3HTR3AKCNH2 | |
| SCHEMBL9867087 | 0.80 | DRD2 (0.40) | DRD4DRD2DRD3HTR3AKCNH2 | |
| SCHEMBL9866922 | 0.77 | DRD2 (0.56) | DRD4DRD2DRD3HTR3AKCNH2 | |
| SCHEMBL11547765 | 0.77 | DRD4 (0.58) | DRD4DRD2DRD3HTR3AKCNH2 | |
| SCHEMBL9867813 | 0.77 | DRD2 (0.55) | DRD4DRD2DRD3HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026858-A | Used for treating nausea, vomating, gastrointestinal disorders and centarl nervous system | WALTON S.A. (ES) | 1991-06-25 | — | — | US | disclosed |