Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866407 | 0.86 | NPSR1 (0.58) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL1358510 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL10248233 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL11720785 | 0.81 | KDM4E (0.44) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL10694441 | 0.80 | KDM4E (0.65) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL15330151 | 0.80 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL15330154 | 0.80 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL16042060 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL521212 | 0.79 | MAPT (0.97) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL1887466 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | claimed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| CN-112209881-B | Emodin oxazole compound and preparation method and application thereof | 西南大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-112209881-A | Emodin azole alcohol compound and preparation method and application thereof | 西南大学 | 2021-01-12 | — | — | CN | disclosed |
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4724234-A | ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION | THERAPEUTICAL SYSTEMS CORP. (US) | 1988-02-09 | — | — | US | disclosed |