Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.56 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336639 | 0.88 | KCNH2 (0.62) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL3885700 | 0.88 | NPBWR1 (0.55) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL5681855 | 0.85 | NPSR1 (0.59) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL6090961 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL30016904 | 0.80 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL1887466 | 0.80 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL30672494 | 0.80 | NPBWR1 (0.58) | KDM4EMAPTNPBWR1KCNH2DGAT1 | |
| SCHEMBL521212 | 0.80 | MAPT (0.97) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL21500616 | 0.80 | NPBWR1 (0.58) | MAPTHSD17B10NPBWR1KCNH2DGAT1 | |
| SCHEMBL16042060 | 0.80 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10734677-B2 | Substituted imidazole and benzimidazole lithium salts | ROBERT BOSCH GMBH (DE) | 2020-08-04 | — | — | US | disclosed |
| WO-2019005216-A1 | SUBSTITUTED IMIDAZOLE AND BENZIMIDAZOLE LITHIUM SALTS | SEEO, INC. (US) | 2019-01-03 | — | — | WO | disclosed |
| CN-105237480-B | A kind of 2 trifluoro methyl benzimidazole compounds and preparation method thereof | 三峡大学 | 2017-12-05 | — | — | CN | disclosed |
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10734677-B2 | Substituted imidazole and benzimidazole lithium salts | KCNJ11, KCNJ1, KCNJ8 | KDM4E 676/4885ALDH1A1 1039/4885HPGD 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.