Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868357 | 0.87 | ALDH1A1 (0.33) | NFE2L2ALDH1A1SMN1; SMN2NR3C1KDM4E | |
| SCHEMBL9867387 | 0.84 | ALDH1A1 (0.35) | NFE2L2ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL9866038 | 0.84 | PDE4A (0.37) | NFE2L2ALDH1A1SMN1; SMN2NR3C1PGR | |
| SCHEMBL9866105 | 0.83 | CA12 (0.33) | NFE2L2ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL9867057 | 0.81 | ALDH1A1 (0.35) | NFE2L2ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL9868058 | 0.80 | ALDH1A1 (0.32) | NFE2L2ALDH1A1SMN1; SMN2NR3C1GAA | |
| SCHEMBL9867677 | 0.78 | CA1 (0.36) | NFE2L2ALDH1A1SMN1; SMN2MMP13 | |
| SCHEMBL9866701 | 0.78 | ALDH1A1 (0.42) | NFE2L2ALDH1A1SMN1; SMN2S1PR1MMP13 | |
| SCHEMBL9868123 | 0.77 | ALDH1A1 (0.33) | NFE2L2ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL9867014 | 0.77 | SCN1A (0.31) | ALDH1A1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |