Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866654 | 0.86 | ALDH1A1 (0.38) | SCN1ASCN5ASCN8AKDM4EALDH1A1 | |
| SCHEMBL9867620 | 0.82 | ADAMTS4 (0.39) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9867057 | 0.81 | ALDH1A1 (0.35) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9868164 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1 | |
| SCHEMBL9866038 | 0.79 | PDE4A (0.37) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9868357 | 0.79 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9866701 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9866248 | 0.78 | LMNA (0.45) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9868123 | 0.77 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9866464 | 0.77 | NFE2L2 (0.33) | KDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |