Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867387 | 0.87 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2GAANFE2L2 | |
| SCHEMBL9866105 | 0.86 | CA12 (0.33) | ALDH1A1SMN1; SMN2GAANFE2L2 | |
| SCHEMBL9868357 | 0.84 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2GAANFE2L2NR3C1 | |
| SCHEMBL9866464 | 0.80 | NFE2L2 (0.33) | ALDH1A1SMN1; SMN2GAANFE2L2NR3C1 | |
| SCHEMBL9867057 | 0.79 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2GAANFE2L2 | |
| SCHEMBL9868123 | 0.78 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2GAANFE2L2 | |
| SCHEMBL9867620 | 0.74 | ADAMTS4 (0.39) | ALDH1A1SMN1; SMN2GAANFE2L2 | |
| SCHEMBL9866046 | 0.74 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NFE2L2NR3C1 | |
| SCHEMBL9866038 | 0.74 | PDE4A (0.37) | ALDH1A1SMN1; SMN2NFE2L2NR3C1 | |
| SCHEMBL9867413 | 0.73 | TRPV3 (0.46) | ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |