Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616241 | 0.87 | KDM4E (0.65) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL19863783 | 0.83 | RAB9A (0.69) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL27867738 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL4932027 | 0.81 | VDR (0.53) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL28063184 | 0.81 | VDR (0.53) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL28125875 | 0.81 | VDR (0.53) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL4727271 | 0.81 | RAB9A (0.66) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL29467866 | 0.80 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL22822638 | 0.80 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL9674712 | 0.80 | VDR (0.58) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015473-A | Beta-lactamase inhibitors | PFIZER INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4826833-A | ANTIBIOTICS | PFIZER INC. (US) | 1989-05-02 | — | — | US | disclosed |