SCHEMBL9866503

SCHEMBL9866503

CC(NC(=O)c1cc(S(=O)(=O)CC2CC2)cc2c1OCCC2)(C1CC1)C1CCCN1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.31
CNR1 P21554 1/20 0.31
RORC P51449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9868286 0.92 SSTR4 (0.31) CNR2CNR1
Hydrochloric Acid SCHEMBL27347878 0.91 SSTR4 (0.30) CNR2CNR1
SCHEMBL27376799 0.79
SCHEMBL27376806 0.78 ADRA2C (0.31)
SCHEMBL27350311 0.77
SCHEMBL9868305 0.77 PARP1 (0.33)
SCHEMBL9822687 0.76 CNR1 (0.30) CNR2CNR1
SCHEMBL9823201 0.76
SCHEMBL9868166 0.75 KEAP1 (0.33)
SCHEMBL9822832 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006570-A Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics LABORATOIRES DELAGRANGE (FR) 1991-04-09 US claimed