SCHEMBL9868286

SCHEMBL9868286

CCS(=O)(=O)c1cc2c(c(C(=O)NC(C)(C3CC3)C3CCCN3)c1)OCCC2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27347878 0.99 SSTR4 (0.30) SSTR4CNR1CNR2
SCHEMBL9866503 0.92 CNR2 (0.31) CNR1CNR2
SCHEMBL27376799 0.84
SCHEMBL9868305 0.84 PARP1 (0.33)
SCHEMBL27376806 0.83 ADRA2C (0.31)
SCHEMBL9822687 0.83 CNR1 (0.30) CNR1CNR2
SCHEMBL27350311 0.79
SCHEMBL9822959 0.74 DRD2 (0.30)
Hydrochloric Acid SCHEMBL9868759 0.74 BACE1 (0.31)
SCHEMBL10368616 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1062144-A The preparation method of benzodihydropyran carboxamide derivatives DELAGRANGE LAB (FR) 1992-06-24 CN claimed
US-5006570-A Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics LABORATOIRES DELAGRANGE (FR) 1991-04-09 US claimed
CN-87100978-A Dihydrobenzofuran-and chroman-carboxamide derivatives, processes for their preparation and their use as neuroleptics 1987-09-16 CN claimed
CN-1062144-A The preparation method of benzodihydropyran carboxamide derivatives DELAGRANGE LAB (FR) 1992-06-24 CN disclosed
CN-87100978-A Dihydrobenzofuran-and chroman-carboxamide derivatives, processes for their preparation and their use as neuroleptics 1987-09-16 CN disclosed