SCHEMBL9866549

SCHEMBL9866549

NCCSCc1ccc2ccccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MC4R P32245 3/20 0.50
MC5R P33032 2/20 0.50
MC3R P41968 2/20 0.47
CYP1A2 P05177 4/20 0.47
CYP2A6 P11509 1/20 0.47
CYP2D6 P10635 3/20 0.46
CYP2C19 P33261 3/20 0.46
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
EPHX1 P07099 1/20 0.40
DAO P14920 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11704765 0.98 LMNA (0.50) LMNASMN1; SMN2MC4RMC5RMC3R
SCHEMBL19825525 0.88 CYP1A2 (0.54) LMNASMN1; SMN2MC4RMC5RMC3R
Succinic Acid SCHEMBL29661250 0.88 CYP1A2 (0.54) LMNASMN1; SMN2MC4RMC5RMC3R
SCHEMBL9456940 0.84 LMNA (0.60) LMNASMN1; SMN2MC4RMC5RMC3R
SCHEMBL11188199 0.81 LMNA (0.48) LMNASMN1; SMN2MC4RMC5RCYP1A2
SCHEMBL14506867 0.79 CYP1A2 (0.53) LMNASMN1; SMN2MC4RMC5RMC3R
SCHEMBL31122366 0.79 SMN1; SMN2 (0.55) LMNASMN1; SMN2MC4RMC5RCYP1A2
SCHEMBL1127606 0.79 SMN1; SMN2 (0.55) LMNASMN1; SMN2MC4RMC5RCYP1A2
Hydrochloric Acid SCHEMBL29661235 0.77 LMNA (0.44) LMNASMN1; SMN2MC4RMC5RMC3R
SCHEMBL9626394 0.77 LMNA (0.44) LMNASMN1; SMN2MC4RMC5RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4035492-A Oral treatment of seborrhea with cysteamine derivatives L'OREAL (FR) 1977-07-12 US claimed
US-20230404947-A1 COMPOSITIONS, METHODS OF TREATMENT, AND CONTAINERS INCLUDING COMPOSITIONS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2023-12-21 US disclosed
US-20230338310-A1 ANTI-VIRAL THERAPY NOVABIOTICS LIMITED (GB) 2023-10-26 US disclosed
US-11771665-B2 Compositions, methods of treatment, and containers including compositions UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-10-03 US disclosed
EP-4157247-A1 ANTI-VIRAL THERAPY Novabiotics Limited (GB) 2023-04-05 EP disclosed
US-11369568-B2 Microparticles comprising a sulphur-containing compound NOVABIOTICS LIMITED (GB) 2022-06-28 US disclosed
WO-2021240145-A1 ANTI-VIRAL THERAPY NOVABIOTICS LIMITED (GB) 2021-12-02 WO disclosed
WO-2021203136-A1 METHODS FOR TREATING HYPERPIGMENTATION AND COMPOSITIONS FOR SAME CHEMISTRYRX (US) 2021-10-07 WO disclosed
US-20210299019-A1 METHODS FOR TREATING HYPERPIGMENTATION AND COMPOSITIONS FOR SAME CHEMISTRYRX (US) 2021-09-30 US disclosed
US-10905660-B2 Microparticles NOVABIOTICS LIMITED (GB) 2021-02-02 US disclosed
US-20170348253-A1 Treatment of Drug-Resistant Microbial Infections NOVABIOTICS LIMITED (GB) 2017-12-07 US disclosed
US-20170348254-A1 MICROPARTICLES NOVABIOTICS LIMITED (GB) 2017-12-07 US disclosed
EP-3197476-A1 USE OF CYSTEAMINE IN TREATING INFECTIONS CAUSED BY YEASTS/MOULDS Novabiotics Limited (GB) 2017-08-02 EP disclosed
WO-2016198842-A1 AN AMINO THIOL FOR USE IN THE TREATMENT OF AN INFECTION CAUSED BY THE BACTERIUM MYCOBACTERIUM SPP. NOVABIOTICS LIMITED (GB) 2016-12-15 WO disclosed
US-20160102052-A1 Use of Cysteamine in Treating Infections caused by Yeasts/Moulds NOVABIOTICS LIMITED (GB) 2016-04-14 US disclosed
WO-2016046524-A1 USE OF CYSTEAMINE IN TREATING INFECTIONS CAUSED BY YEASTS/MOULDS NOVABIOTICS LIMITED (GB) 2016-03-31 WO disclosed
US-5021431-A H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion HEUMANN PHARMA GMBH & CO. (DE) 1991-06-04 US disclosed
EP-0199845-B1 IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM HEUMANN PHARMA GMBH & CO (DE) 1990-08-01 EP disclosed
EP-0199845-A1 Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them HEUMANN PHARMA GMBH & CO (DE) 1986-11-05 EP disclosed
US-4139635-A Cysteamine derivatives for oral treatment of seborrhea L'OREAL (FR) 1979-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338310-A1 ANTI-VIRAL THERAPY MAVS, HAVCR2, IRF3 LMNA 3342/4885SMN1; SMN2 2770/4885MC4R 2699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.