Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.71 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.67 |
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866577 | 0.94 | SIGMAR1 (0.79) | SIGMAR1SCN5ALTA4HHRH3SLC6A3 | |
| SCHEMBL13661556 | 0.94 | SIGMAR1 (0.79) | SIGMAR1SCN5ALTA4HHRH3SLC6A3 | |
| SCHEMBL83687 | 0.86 | SIGMAR1 (0.86) | SIGMAR1LTA4HHRH3SLC6A3GRIN2B | |
| SCHEMBL5708589 | 0.85 | SIGMAR1 (0.73) | SIGMAR1LTA4H | |
| SCHEMBL16511543 | 0.85 | SCN5A (0.72) | SIGMAR1SCN5ALTA4HHRH3 | |
| SCHEMBL113897 | 0.84 | SIGMAR1 (0.96) | SIGMAR1LTA4HHRH3SLC6A3GRIN2B | |
| Ammonia Solution, Strong SCHEMBL28704893 | 0.84 | SIGMAR1 (0.83) | SIGMAR1LTA4HHRH3SLC6A3GRIN2B | |
| SCHEMBL10601122 | 0.84 | SIGMAR1 (0.96) | SIGMAR1LTA4HHRH3SLC6A3GRIN2B | |
| Hydrochloric Acid SCHEMBL8037018 | 0.84 | SIGMAR1 (0.83) | SIGMAR1LTA4HHRH3SLC6A3GRIN2B | |
| SCHEMBL25809972 | 0.84 | SCN5A (0.68) | SIGMAR1SCN5AHRH3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219914-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | Nuray Chemicals Private Limiited (IN) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219914-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | PITHD1, MLN, TPP1 | SIGMAR1 3365/4885SCN5A 1031/4885LTA4H 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.