Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9867941 | 0.99 | BACE1 (0.31) | DRD2DRD3BACE1 | |
| SCHEMBL10812508 | 0.83 | PARP1 (0.32) | BACE1 | |
| SCHEMBL10810689 | 0.82 | CA1 (0.32) | BACE1 | |
| SCHEMBL10805518 | 0.77 | PARP1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL10807994 | 0.77 | BRD4 (0.37) | BACE1 | |
| SCHEMBL9868152 | 0.76 | PARP1 (0.32) | — | |
| SCHEMBL3314494 | 0.76 | DRD2 (0.53) | DRD2DRD3LMNAADRA2AALOX15 | |
| SCHEMBL21054909 | 0.76 | DRD2 (0.53) | DRD2DRD3LMNAADRA2AALOX15 | |
| SCHEMBL21055572 | 0.76 | DRD2 (0.53) | DRD2DRD3LMNAADRA2AALOX15 | |
| SCHEMBL9867849 | 0.76 | PARP1 (0.37) | DRD2DRD3LMNAADRA2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |