Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472047 | 0.81 | MAOA (0.43) | MAOACES1BCHEALDH1A1CASP6 | |
| SCHEMBL472046 | 0.76 | MAOA (0.43) | MAOACES1BCHEALDH1A1CASP6 | |
| SCHEMBL18457362 | 0.74 | MAOA (0.38) | MAOACES1BCHEALDH1A1CASP6 | |
| SCHEMBL23738688 | 0.73 | CYP2A6 (0.41) | MAOACES1BCHEALDH1A1CASP6 | |
| Fluorene SCHEMBL29478468 | 0.72 | MAOA (0.68) | MAOACES1BCHEALDH1A1CASP6 | |
| Fluorene SCHEMBL29355380 | 0.72 | MAOA (0.68) | MAOACES1BCHEALDH1A1CASP6 | |
| Fluorene SCHEMBL31388525 | 0.72 | MAOA (0.68) | MAOACES1BCHEALDH1A1CASP6 | |
| Fluorene SCHEMBL545861 | 0.72 | MAOA (0.68) | MAOACES1BCHEALDH1A1CASP6 | |
| Fluorene SCHEMBL8180 | 0.72 | MAOA (0.68) | MAOACES1BCHEALDH1A1CASP6 | |
| SCHEMBL22506913 | 0.72 | MAOA (0.43) | MAOACES1BCHEALDH1A1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983324-A | NONLINEAR OPTICAL MATERIALS AND DISPLAY DEVICE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-08 | — | — | US | claimed |