Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CASP6 | P55212 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472047 | 0.84 | MAOA (0.43) | MAOABCHECES1ALDH1A1KMT2A | |
| SCHEMBL9866710 | 0.74 | MAOA (0.46) | MAOABCHECES1ALDH1A1CDK8 | |
| SCHEMBL4668953 | 0.74 | MAOA (0.56) | MAOABCHECES1ALDH1A1CDK8 | |
| SCHEMBL472046 | 0.71 | MAOA (0.43) | MAOABCHECES1ALDH1A1CDK8 | |
| SCHEMBL22699113 | 0.69 | ALDH1A1 (0.40) | MAOABCHECES1ALDH1A1CDK8 | |
| SCHEMBL11143500 | 0.67 | CYP1A2 (0.61) | MAOABCHECES1ALDH1A1KMT2A | |
| SCHEMBL10773270 | 0.67 | MAOA (0.43) | MAOABCHECES1ALDH1A1CDK8 | |
| SCHEMBL9915574 | 0.67 | CES1 (0.61) | MAOABCHECES1ALDH1A1KMT2A | |
| SCHEMBL29795069 | 0.66 | MAOA (0.46) | MAOABCHECES1ALDH1A1CDK8 | |
| SCHEMBL5027873 | 0.66 | MAOA (0.46) | MAOABCHECES1ALDH1A1CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017020030-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITION ASSOCIATED WITH UBIQUITINATION-PROTEASOME SYSTEM | TAIPEI MEDICAL UNIVERSITY (TW) | 2017-02-02 | — | — | WO | disclosed |