Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 14/20 | 0.60 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP7 | P09237 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866742 | 1.00 | CTSD (0.60) | CTSDIDEMMP1MMP9MMP7 | |
| SCHEMBL7385411 | 0.78 | CTSD (0.45) | CTSDIDEMMP1MMP9MMP7 | |
| SCHEMBL8745896 | 0.75 | ITGB1 (0.42) | CTSDMMP1MMP9MMP7MMP3 | |
| SCHEMBL5963363 | 0.74 | CTSD (0.40) | CTSDMMP1MMP9MMP7MMP3 | |
| SCHEMBL13969675 | 0.72 | — | — | |
| SCHEMBL3743995 | 0.72 | — | — | |
| SCHEMBL14069032 | 0.72 | — | — | |
| SCHEMBL30934204 | 0.72 | CTSD (0.48) | CTSD | |
| SCHEMBL9491181 | 0.70 | CTSD (0.49) | CTSDMMP1MMP9MMP7MMP3 | |
| SCHEMBL8970758 | 0.70 | CTSD (0.39) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061808-A | 2-oxo-1-pyrrolidine carboxylic acid esters | WARNER-LAMBERT COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-4876343-A | Process for statine and statine analogs | WARNER-LAMBERT COMPANY (US) | 1989-10-24 | — | — | US | disclosed |