Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190390 | 0.79 | MMP1 (0.36) | MMP1MMP9MMP7MMP3PLG | |
| SCHEMBL5963599 | 0.78 | NOS1 (0.38) | MMP1MMP9MMP7MMP3PLG | |
| SCHEMBL6966406 | 0.78 | CTSD (0.40) | MMP1MMP9MMP7MMP3PLG | |
| SCHEMBL9866742 | 0.75 | CTSD (0.60) | MMP1MMP9MMP7MMP3CTSD | |
| SCHEMBL9866747 | 0.75 | CTSD (0.60) | MMP1MMP9MMP7MMP3CTSD | |
| SCHEMBL19444341 | 0.74 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL30259736 | 0.74 | PLG (0.36) | MMP1MMP9MMP7MMP3PLG | |
| SCHEMBL3631882 | 0.74 | PLG (0.36) | MMP1MMP9MMP7MMP3PLG | |
| SCHEMBL3632699 | 0.74 | PLG (0.36) | MMP1MMP9MMP7MMP3PLG | |
| SCHEMBL1775957 | 0.72 | PLG (0.38) | MMP1MMP9MMP7MMP3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2121963-A | — | — | None | — | — | JP | disclosed |
| EP-0519763-B1 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO PERFUMERY CO LTD (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5502221-A | HYPOTENSIVE INTERMEDIATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5442105-A | Catalytic hydrogenation, epoxidation, reacting product with trialkylsilyl azide in the presence of a Lewis acid, hydrogenolysis | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0519763-A2 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-12-23 | — | — | EP | disclosed |
| JP-H02121963-A | 4-CYCLOHEXYLMETHYL-2-AZETIDINONE DERIVATIVE AND PRODUCTION THEREOF | KISSEI PHARMACEUT CO LTD | 1990-05-09 | — | — | JP | disclosed |