Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558285 | 0.88 | GABRP (0.42) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL10557783 | 0.88 | GAA (0.35) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL10558290 | 0.88 | GABRP (0.42) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL10562596 | 0.85 | CES2 (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL10564163 | 0.83 | CA12 (0.35) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL7298595 | 0.80 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL10560151 | 0.79 | MAPT (0.39) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7288991 | 0.79 | GABRP (0.40) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7289168 | 0.79 | CES2 (0.33) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL9865071 | 0.77 | MCHR1 (0.38) | PDE4APDE4BPDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |