Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867405 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL20232999 | 0.79 | EPHX1 (0.41) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL27705911 | 0.79 | EPHX1 (0.41) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL14219302 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL9867091 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL23573418 | 0.77 | EPHX1 (0.42) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL9868982 | 0.77 | EPHX1 (0.52) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL18474342 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL14098332 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| SCHEMBL14543527 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |