Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867091 | 0.95 | SMN1; SMN2 (0.73) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9866491 | 0.93 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28051161 | 0.91 | SMN1; SMN2 (0.74) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL4427177 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9866968 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL6850969 | 0.82 | SMN1; SMN2 (0.94) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9868982 | 0.80 | EPHX1 (0.52) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL23736058 | 0.79 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL3076504 | 0.79 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL2377367 | 0.79 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |