Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866987 | 0.94 | EBP (0.36) | HRH2RAB9AHRH4 | |
| SCHEMBL9866705 | 0.89 | SCN5A (0.40) | HRH2HRH4 | |
| SCHEMBL9865305 | 0.88 | NPY1R (0.41) | — | |
| SCHEMBL9866078 | 0.87 | EPHX2 (0.39) | — | |
| SCHEMBL9865291 | 0.86 | HRH2 (0.36) | HRH2HRH4 | |
| SCHEMBL9866163 | 0.85 | RAB9A (0.37) | RAB9A | |
| SCHEMBL9865299 | 0.84 | RAB9A (0.38) | RAB9A | |
| SCHEMBL9865765 | 0.84 | RAB9A (0.47) | HRH2RAB9AHRH4 | |
| SCHEMBL7297991 | 0.84 | NPY1R (0.39) | — | |
| SCHEMBL9866425 | 0.83 | RAB9A (0.42) | HRH2RAB9AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | claimed |
| EP-0199845-B1 | IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |