Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10445022 | 0.99 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9865213 | 0.88 | HRH3 (0.37) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9865646 | 0.86 | MCHR1 (0.40) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9866678 | 0.86 | HRH3 (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| Iodide SCHEMBL10445057 | 0.85 | HRH3 (0.43) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9867236 | 0.81 | MCHR1 (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9866270 | 0.81 | MCHR1 (0.42) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9867683 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9866493 | 0.79 | HRH3 (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9865428 | 0.79 | MCHR1 (0.38) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |